DuPont Introduces New
Silicone Blends To Address Skin Conditions
DuPont has introduced new low-cyclosiloxane silicone
elastomer blends and silicone resin blends in response to growing consumer
desires for products that address a range of troubling skin conditions.
These new topical excipient blends also address the
market’s need to comply with evolving REACH regulatory compliance demands and to
support the shared commitment of DuPont and its customers to the United Nations
Sustainable Development Goals (UN SDGs), particularly UNSDG No. 3 – Good Health
and Well Being – which calls for protecting human health and wellbeing for all
people at all ages.
Over-the-counter topical and medical products to
address scars, actinic keratosis, atopic dermatitis, psoriasis and other skin
conditions are proliferating to meet consumer desires to feel good at every age
without compromising skin protection and drug delivery efficiency. Regulations
on consumer healthcare products continue to evolve to ensure safety and minimise
IDuPont Liveo has developed four new low-cyclosiloxane
silicone topical excipient blends. These products are designed to help customers
meet the substance of very high concern (SVHC) threshold for concerned
cyclosiloxanes – below 0.1% – proposed by REACH regulation (EC) No. 1907/2006.
Potential uses for silicone elastomer blends include
topical drug delivery formulations for prescription and over-the-counter
products that may improve patient compliance due to their unique sensory feel,
including creams for conditions such as atopic dermatitis, psoriasis, and scar
and pain management, as well as creams and gels that offer a mattifying effect
for acne applications. Silicone elastomer blend technologies also are known for
their effectiveness in support of drug release or drug permeation in topical
semi-solid formulations thereby providing options to formulators.
Liveo silicone resin blends can be incorporated
easily into many product forms, including creams for skin barrier applications,
sprays that offer ease of application and protect the skin, and gels for novel
product forms in challenging skin conditions. Target indications include skin
barriers and protective films for ostomy care; liquid bandages, skin barriers
and scar management for wound care; UV protection and sunscreens for skin care;
and drug delivery therapy for acne, actinic keratosis, antifungal and pain
management in dermal care.
DuPont serves a broad spectrum of consumer and
medical topical healthcare applications, from over-the-counter to prescription.