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DuPont Introduces New Silicone Blends To Address Skin Conditions

DuPont has introduced new low-cyclosiloxane silicone elastomer blends and silicone resin blends in response to growing consumer desires for products that address a range of troubling skin conditions.

Skin conditions

These new topical excipient blends also address the market’s need to comply with evolving REACH regulatory compliance demands and to support the shared commitment of DuPont and its customers to the United Nations Sustainable Development Goals (UN SDGs), particularly UNSDG No. 3 – Good Health and Well Being – which calls for protecting human health and wellbeing for all people at all ages.

Over-the-counter topical and medical products to address scars, actinic keratosis, atopic dermatitis, psoriasis and other skin conditions are proliferating to meet consumer desires to feel good at every age without compromising skin protection and drug delivery efficiency. Regulations on consumer healthcare products continue to evolve to ensure safety and minimise public risk.

IDuPont Liveo has developed four new low-cyclosiloxane silicone topical excipient blends. These products are designed to help customers meet the substance of very high concern (SVHC) threshold for concerned cyclosiloxanes – below 0.1% – proposed by REACH regulation (EC) No. 1907/2006.

Potential uses for silicone elastomer blends include topical drug delivery formulations for prescription and over-the-counter products that may improve patient compliance due to their unique sensory feel, including creams for conditions such as atopic dermatitis, psoriasis, and scar and pain management, as well as creams and gels that offer a mattifying effect for acne applications. Silicone elastomer blend technologies also are known for their effectiveness in support of drug release or drug permeation in topical semi-solid formulations thereby providing options to formulators.

Liveo silicone resin blends can be incorporated easily into many product forms, including creams for skin barrier applications, sprays that offer ease of application and protect the skin, and gels for novel product forms in challenging skin conditions. Target indications include skin barriers and protective films for ostomy care; liquid bandages, skin barriers and scar management for wound care; UV protection and sunscreens for skin care; and drug delivery therapy for acne, actinic keratosis, antifungal and pain management in dermal care.

DuPont serves a broad spectrum of consumer and medical topical healthcare applications, from over-the-counter to prescription.







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